Cady Heron is a hit with The Plastics, the A-list girl clique at her new school, until she makes the mistake of falling for Aaron Samuels, the ex-boyfriend of alpha Plastic Regina George.
Lindsay Lohan, Rachel McAdams, Lacey Chabert, Amanda Seyfried, Lizzy Caplan, Daniel Franzese, Jonathan Bennett, Tina Fey, Tim Meadows, Amy Poehler, Ana Gasteyer, Neil Flynn, Rajiv Surendra, Elana Shilling, Graham Kartna, Ely Henry, David Aherne, Ayo Agbonkpolo, Molly Shanahan, Jonathan Malen, Jeff Moser, Miranda Edwards, Les Porter, Eve Crawford, Jack Newman, Michelyn Emelle, Bathsheba Garnett, Ky Pham, Danielle Nguyen, Daniel DeSanto, Alisha Morrison, Chris Anton, Dwayne Hill, Diego Klattenhoff, Jan Caruana, Wai Choy, Julia Chantrey, Jacky Chamberlain, Olympia Lukis, Stefanie Drummond, Kristen Bone, Jessie Wright, Tyson Fennell, Stephan Dickson, Andreja Punkris, Noelle Boggio, Jordan Dawe, Alexandra Stapley, Laura de Carteret, Nicole Crimi, Erin Norah Thompson, Dan Willmott, Michelle Hoffman, Valerie Casault, Sharron Matthews, Jo Chim, Randi Lee Butcher, Erin Jarvis, Kaylen Christensen, Jill Morrison, David Sazant, Clare Preuss, Bruce Hunter, Megan Millington, Tara Shelley, Shannon Todd, David Reale, Krysta Carter